|
KMID : 0614620040430050304
|
|
Korean Journal of Gastroenterology
2004 Volume.43 No. 5 p.304 ~ p.309
|
|
|
Dose Ascites Mean More Severe Crohn`s Disease?
|
|
이재욱/Lee JU
김영호/이선영/김갑현/정정환/김경희/손희정/이풍렬/김재준/이종철/Kim YH/Lee SY/Kim KH/Chung CH/Kim KH/Son HJ/Rhee PL/Kim JJ/Rhee JC
|
|
|
Abstract
|
|
|
Background/Aims: Ascites that can be induced by various causes is not a rare finding in Crohn`s disease. The clinical implication of ascites in Crohn`s disease remains unknown in the cases without any specific cause of ascites except Crohn`s disease itself. The purpose of this study was to investigate the clinical implication and characteristics of ascites in Crohn`s disease.
Methods: We reviewed the medical records of the patients with Crohn`s disease who underwent abdominal CT scan. Patients were categorized into two groups: patients with ascites (22 cases) and without ascites (23 cases). We compared clinical features, disease activities and clinical courses of the two groups.
Results: Serum albumin level was significantly lower and the C-reactive protein level was significantly higher in the ascites group than in the control group. Harvey & Bradshaw index was significantly higher in the ascites group (8.32±2.51) than in the control group (6.09±2.07) (p＝0.002). The average dose of prednisolone was higher in the ascites group. On the other hand, there was no significant difference in the number of cases requiring surgery due to complication between two groups.
Conclusions: Our results suggest that the presence of ascites in Crohn`s disease is associated with increased disease activity and inflammations requiring more aggressive treatment.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|